Epistane (Methylepitiostanol, Epistane) is an anabolic androgenic steroid (AAS) best known by the trade name Havoc.
It is an oral, 17-alpha-alkylated steroid, a derivative of the steroid epitiostanol (epitiostanol). Epitiostanol was registered in Japan as an injectable anti-estrogen and anti-cancer drug in 1977. The injectable version was called Thiodrol and the 17b-(1-methoxy)cyclopentyl ester version of epitiostanol, also called mepitiostane, was for oral use and had the trade name Thioderon. Mepitiostane was described as analogous to tamoxifen when used as an anti-estrogen. However, it was immediately observed that in addition to its anti-estrogenic properties, Epithiostanol also exhibited anabolic properties.
Steroid Profile
Anabolic activity - 1100% of testosterone
Androgenic activity - 91% of testosterone
Aromatization (conversion to estrogens) - none
Directions for Use - Oral (tablets)
Liver toxicity - moderate/weak
The elimination half-life - 6-8 hours.
The oral "commercial" version, released on the American market around 2007, was no longer an ester, but a simple 17-alpha alkylated version of epitiostanol. The designer steroid also, like the Japanese drug, shows anti-estrogenic qualities. The ratio of anabolic to androgenic activity in this steroid is 1100 to 91. Epistane is a derivative of DHT, so it does not aromatize and is not converted by 5a-reductase. Epistane is quite close to Anavar in terms of its effects. One of the positive qualities is that it suppresses its own estrogen and also weakly suppresses the production of its own testosterone. Another advantage is fat burning, due to the fact that the steroid suppresses estrogen production, but because of dehydration, joint problems may appear. Since the steroid is 17-alpha alkylated, it carries liver toxicity, but it is considered one of the "mildest" in its class.
Verdict.
Epistan is a steroid similar to Anavar. Epistane is moderately/weakly toxic to the liver. It also works as an anti-estrogen, so it burns fat, and weakly suppresses the hypothalamic-pituitary-ovarian axis, but can be harmful to the joints.
